Moonwood Garden

You know, something that never sat quite right with me is the defense of Bells Hells constantly having the same argument as "realistic" not just because "realistic" doesn't mean "compelling to watch"...but also because this isn't actually realistic in like, functional groups.

I was involved in a number of clubs in college and was on the board of several; I am on an alumni board for a university club I was in as an undergrad. I've been in a leadership role in an independent congregation and a member of several political interest groups in adulthood. I've also been an indirect manager (think team lead for a specific project but not the person people report to regularly) in a professional setting - and those are just formalized settings and not just hanging out with friends or smaller group projects.

The idea that it's normal and relatable to have a group of people who just endlessly and repeatedly provide their perspective and argument without any sort of resolution is one of those "wait, you live like this?" moments. During debates, such as for board elections or in one case, a very emotionally heightened decision to eject a member who had been credibly accused of wrongdoing against another, the phrase that got used once everyone had had a chance to talk and address any questions was, essentially, "will further discussion change anyone's mind." Because that is ultimately the purpose of discussion - to make sure everyone has all the information, and to allow everyone an opportunity to speak their piece in the service of ultimately coming to a decision. Discussion about a course of action is not an end point in itself, and there comes a time where you have to say "your feelings are valid but your talking isn't going to change anyone's mind at this point and we need to move forward in some manner."

Romanticizing endless tiresome indecision feels no different to me than romanticizing some other utterly unnecessary behavior like, I don't know, hustle culture. If your friends can't decide on a restaurant for 2 hours (or 2 months) then either do a rotating schedule, decide to meet for coffee/drinks/a bring-your-own-stuff picnic, or if this is food as part of a longer outing, don't be afraid to split up for a small part of it. If you can't decide what to do in a group project, assign a leader or take it to a vote and provide a clear tie-break condition. Flip a coin, if nothing else can be done. But you do not have to live like this; really, it just takes one person to speak up and say "we've been talking in circles for two hours and I'm exhausted; does anyone have new information or a concern that wasn't brought up or is it time to call it?" And your life will be immeasurably better the day you decide to be that person whenever relevant.

This is my gift for a happy 2023. I converted the 24 items to base game

DOWNLOAD(rar)

DOWNLOAD (zip)

consider to buy me a coffee <3

Science Friday

Trees And Shrubs Are Burying Prairies Of The Great Plains

A “green glacier” of trees and shrubs is sliding across the region, burying some of the most threatened habitat on the planet.

Excerpt from this story from Science Friday:

Flint Hills rancher Daniel Mushrush estimates that his family has killed maybe 10,000 trees in the past three years.

It’s a start. But many more trees still need to fall for the Mushrushes to save this 15,000 acres of rare tallgrass prairie.

Whenever other work on the property can wait, Daniel and his brother, Chris, don helmets and earplugs, grab their tools and pick up where they left off.

“It’s a lot of old-fashioned chainsaw work,” Daniel Mushrush said. “Walking rocky ridges and cutting down trees.”

The Mushrush family is beating back a juggernaut unleashed by humans — a Green Glacier of trees and shrubs grinding slowly across the Great Plains and burying some of the most threatened habitat on the planet.

This blanket of shrublands and dense juniper woods gobbling up grassland leads to wildfires with towering flames that dwarf those generated in prairie fires.

It also eats into ranchers’ livelihoods. It smothers habitat for grassland birds, prairie fish and other critters that evolved for a world that’s disappearing. It dries up streams and creeks. New research even finds that, across much of the Great Plains, the advent of trees actually makes climate change worse.

Now a federal initiative equips landowners like Mushrush with the latest science and strategies for saving rangeland, and money to help with the work.

Satellite imagery and a better understanding of how trees and shrubs spread could help landowners replace a losing game of whack-a-mole with a more systematic course.

Mushrush calls the approach, promoted by the Natural Resources Conservation Service’s Great Plains Grassland Initiative with guidance from the University of Nebraska-Lincoln, a morale builder.

“It works,” the third-generation rancher said. “We’re still overwhelmed with how to do this on 15,000 acres — but we have a plan.”

Each time he thinks about the Manhattan area, which is much more infested with juniper woods and seas of sumac, wild plum and dogwood thickets, he feels the threat creeping toward his home in Chase County.

“If a coral reef is worth saving, if some pristine mountain stream is worth saving, then so are the Flint Hills,” he said. “It’s not easy work, but it’s worthy work.”

happy year of the 🐍

Lady Jiang (Xue Fangfei)'s outfit details at the Welcome Banquet for the Emperor of Great Zhao

THE DOUBLE | 墨雨云间 Episode 31

spice ponytail

took the ponytail from the high school pack and put it over the shoulder :+)

** apologies for the day late post, i’ve been working on my midterms and it slipped my mind

bgc

hat compatible

all 24 ea swatches

spider accessory for halloween in hats :+) not in preview cause ik some of y’all got arachnophobia

dl

Bro bro bro I just figured out if you do double if an emoji you get an Extra Mood of that emoji. This is 🥺🥺

Sutch a discovery is worthy of an emoji board

Replaying Cyberpunk 2077, I am increasingly enjoying the concept of Johnny Silverhand. More RPGs should feature an intangible NPC who accompanies you on your adventures, is a highly opinionated asshole, and provides no assistance whatsoever. What's Johnny going to do today? Is he going to spice up an otherwise boring quest with a private-eye monologue? Is he going to lie to me about his own life to make me lose a Johnny Silverhand trivia contest? Is he going to give me a poetic and beautiful speech about living on despite the odds? Is he going to launch into an unhinged political rant? Is he going to somehow inexplicably make this conversation about his dick? I don't know, I don't think he does either. V is trying to deal with The Horrors of Cyberpunk and also their own impending death and ALSO live the life of an unstoppable supermerc and they're stuck in a torment nexus Get Along Sweater with a dead terrorist rockerboy who sucks in every way imaginable and it's great.

How Does The Drug Got Excreted / Eliminated From The Body?

Drug excretion is an important process in pharmacology, encompassing the elimination of pharmaceutical substances from the body. While the ultimate elimination of all drugs is inevitable, the specific pathways involved can vary significantly. Some drugs undergo extensive metabolic transformations before being excreted, while others are expelled from the body in their original form.

The kidneys play a central role in excreting water-soluble substances, effectively filtering them from the bloodstream. Meanwhile, the biliary system handles drugs that remain unabsorbed from the gastrointestinal tract, providing an alternative route for elimination. Although excretion through auxiliary channels such as the intestines, saliva, sweat, breast milk, and lungs is typically minimal, certain volatile anesthetics and residual drug traces in breast milk can have notable impacts, particularly on vulnerable populations such as infants.

Renal excretion constitutes a significant portion of drug elimination, accounting for approximately 20% of the plasma that is filtered through the glomeruli. While most water and electrolytes are reabsorbed back into circulation, polar compounds like drug metabolites are excreted predominantly in urine. However, it’s important to note that renal excretion tends to decrease with age, necessitating careful dosage adjustments for elderly patients to mitigate potential adverse effects.

Numerous factors influence the process of renal excretion, including the extent of protein binding, the degree of drug ionization affecting reabsorption rates, fluctuations in urine pH that can alter excretion dynamics, and the impact of metabolic inhibitors on tubular secretion mechanisms.

Biliary elimination, on the other hand, occurs when drugs traverse the biliary epithelium via active transport mechanisms. However, this process is not without limitations, as transporter saturation can impose constraints on drug excretion rates. Typically, larger molecules containing polar and lipophilic groups are excreted through bile, while smaller molecules tend to favor renal elimination pathways.

In addition to renal and biliary routes, drugs may also be eliminated to varying extents through auxiliary pathways such as saliva, tears, feces, sweat, and exhalation. While the quantities eliminated through these routes are generally minimal, drug excretion in breast milk can pose significant concerns for lactating mothers, potentially exposing nursing infants to pharmacological agents.

Understanding the pharmacokinetic parameters governing drug excretion is paramount for optimizing therapeutic regimens and minimizing the risk of adverse effects. Key parameters include the rate of elimination, clearance, elimination rate constant, and biologic half-life for drugs undergoing first-order elimination kinetics.

In conclusion, drug excretion represents a broad process influenced by a myriad of factors, necessitating comprehensive consideration to ensure the safe and efficacious use of pharmacotherapy.

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