Suffering Is Always ‘Optional‘

On Genetic Engineering

Remember when I asked for ressources on this? You seemed kind of interested so here is some of the ones I liked - some are in Portuguese and one is in Spanish tho, long live Nuestra América.

I might update it when my friends send me their part of the project. 

Reading

YourGenome whole website (x)

National Human Genome Institute website which @cancerbiophd recomended to me - thank you again, it was a great start (x)

Nature: CRISPR gene editing is just the begining (x)

Wyss Institute: Gene drive FAQ (x)

Genetic Home Reference guide sheets (x)

Apostila de Biologia 7 do Hexag Medicina - pgs. 156-179 (x)

Uol: Tudo que você precisa saber sobre CRISPR (x)

Site do Conselho de Informação sobre Biotecnologia (x)

TED talks

TED Ed: How to sequence the human genome - Mark J. Kiel

TED Ed: The race to sequence the human genome - Tien Nguyen

TED: How CRISPR lets us edit our DNA - Jennifer Doudna (who is one of the two women who discovered CRISPR-CAS9 by the way)

TED: Gene editing can now change an entire species forever - Jennifer Kahn

TED: What you need to know about CRISPR - Ellen Jorgensen

TED: How we’re harnessing nature’s hidden superpowers - Oded Shoseyo

Short videos

Unlocking Life’s Code: The Animated Genome (x)

Kurzgesagt: Genetic Engineering Will Change Everything Forever - CRISPR (x) Are GMO Good or Bad? Genetic Engineering & our food (x) Genetic Engineering and Diseases - Gene Drvie & Malaria (x) (They’re all very partial to defending genetic engineering, so you get just one side)

Crash Course: DNA: Structure and Replication (x) DNA: Hot Pockets & The Longest Word Ever (x)

N. Garcia:  Composición del genoma Humano (x)

Biologia Total com prof. Jubilut: Mosquito da dengue transgênico (x)

Documentaries

BBC: Playing God

PBS: Cracking your genetic code

GMO OMG (it’s a food conspiracy one I’ll tell you that but it’s intersting)

Alan Turing, Cybernetics and the Secrets of Life

Alan Turing, Cybernetics and the Secrets of Life

Another outstanding mini-documentary from Aaron and Melissa Dykes which explains more about the history of scientific mind control.

Expansion of ideas on cybernetics, and an analysis in Alan Turing’s role in not only creating Intelligent Machinery, but his little-known role in probing the chemical formation of genetic/biological life through morphogenesis.

Quoted Sources & Recommended Reading: -Br…

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Bioinformatics/ Genomics

Genomics:

What is Genomics?

In 1970s Scientist Found the DNA Series of Simple Living Life. It is Branch Of Science, Based on Anatomy, Drawing, Function, Progress, and Modification of Genome. Genomics is Complete Study of the Genomes of Creatures. A Genome is Entire Set of Creatures DNA, Containing All of Its Genes. Its Key Task is Find The Complete Series of DNA or Structure of the Molecules that Build the DNA and the Chemical Chain Between The DNA Molecules. DNA Sequencing Knowledge is Not Only Very essential For The Biological Research But Equally Important in Medical, Medicine, Biotechnology & In Forensic Research etc.

Following are the Key Genomic Research Areas:

1. Meta-Genomics: MetaGenomics is Study of Genetic Substance Which is Gain or Cultivated From Environmental Pattern/Sample. It is Also Known as Ecogenomics, Community Genomics, and Environmental Genomics.

2. Human Genomics: As Name Suggested Human Genomics Is Concentrate on Study of Human Genome Sequence. The Human Genomics is the Entire Set of Nucleic Acid Sequences for Humans, It Found in DNA Within the Pair of 23 Chromosomes in Cell Nuclei and Small DNA Molecule Found separately in Mitochondria.

3. Bacteriophage Genomics: It is Also Known As Phage, it is Study of Genomics Which Infect Bacteria. Phages are ubiquitous viruses, found wherever bacteria Occurs. Bacteria Found in Soil or the animal’s intestines.

4. Pharmacogenomics: This is Branch Of Genomics Studies, Learn About the Impact of Genetic Changes on the Drugs Efficiency and Toxicity, and Plays Very Key Role in Optimization of Medicine Therapy.

5. Cyanobacteria genomics: This is Area of genomic Investigation is Focusing on the study of cyanobacteria, a phylum of bacteria which get Strength through photosynthesis.

Bioinformatics:

What is Bioinformatics?

Bioinformatics is the Application of Information Technology, Used to Generate Methods and Software Tool For getting Knowledge of Biological data or Living Things. It is Used For Solving Biological Problems.

Bioinformatics is helpful for Create and Implements Computer Programs That Gives Access to Handle, Use and Manage the Information. it is Also Helpful to Develop New Algorithms and Statical Measures That Is Very Useful to Access Large Data.

1. Functional Gene Annotations / Genome Annotation: Gene Annotation is the Action of recognizing the Place of Genes and Entire Coding Zone in a Genome and Find What Those Genes Actually Do.

There Are Three Main Steps For Genome Annotation:

a. Recognize Section of Genome That does not Code For Proteins.

b. Recognise Elements of the  Genome, A action Called Gene Prediction.

c. Connect Biological Information to These Elements.

2. Next-generation sequencing (NGS): It is Fresh Process for Sequencing Genome at High Speed & Less Cost. Next Generation Sequencing  Also Called Second Generation Sequencing(SGS) or Massively Parallel Sequencing(MPS). NGS Generate a Large Amount of Sequence Data. NGS Plays Key Role in the Big Y Test From Family Tree DNA & Y Prime, Y-Elite & While Genome Test From Full Genomes Corporation. The Mitochondrial DNA full Series test uses next-generation sequencing technology (NGS).

3. Gene / Orf Prediction: An Gene/ Orf Prediction is the Element of Reading Frame That Has Capacity to Translated.

4. Genome alignment and Analysis: In Bioinformatics, Sequence Analysis is the Action of Subject to RNA, & DNA. Methods applied for Sequence Alignment, Searches Opposite Biological Database.

5. Multiple sequence alignment: MSA is Normally the Alignment of Three Or More than three Biological Sequences of Equal Length, Generally Protein, RNA & DNA.

6. BLAST / BLAT Data Analysis: Blat is Pairwise Sequence Alignment Algorithm Was Created By Jim Kent At UCSC in the 2000s to Help the Assembly & Notation of Human Genome.

7. Comparative Genomics: Comparative Genomics is an area of Biological Research in WhichGenomis Characteristics of Distinct Creatures are Compared. The Genomic Characteristics Consist the DNA Sequence, Gene Order, Genes, Regulatory Sequences & Another Genomics Landmark.

8 Earth years are roughly equal to 13 Venus years, meaning the two planets approximately trace out this pattern with amazing symmetry as they orbit the Sun.

Key revelations from the Paradise Papers

1) Millions of pounds from the Queen’s private estate has been invested in a Cayman Islands fund – and some of her money went to a retailer accused of exploiting poor families.

2) Prince Charles’s estate made a big profit on a stake in his friend’s offshore firm.

3) Extensive offshore dealings by Donald Trump’s cabinet members, advisers and donors, including substantial payments from a firm co-owned by Vladimir Putin’s son-in-law to the shipping group of the US commerce secretary, Wilbur Ross.

4) Twitter and Facebook received hundreds of millions of dollars in investments that can be traced back to Russian state financial institutions.

5) The tax-avoiding Cayman Islands trust managed by the Canadian prime minister Justin Trudeau’s chief moneyman.

6) The Formula One champion Lewis Hamilton avoided taxes on a £17m jet using an Isle of Man scheme.

7) A previously unknown $450m offshore trust that has sheltered the wealth of Lord Ashcroft.

8) Oxford and Cambridge and top US universities invested offshore, with some of the money going into fossil fuel industries.

9) The man managing Angola’s sovereign wealth fund invested it in projects he stood to profit from.

10) Apple secretly moved parts of its empire to Jersey after a row over its tax affairs.

11) How the sportswear giant Nike stays one step ahead of the taxman.

12) The billions in tax refunds by the Isle of Man and Malta to the owners of private jets and luxury yachts.

13) Offshore cash helped fund Steve Bannon’s attacks on Hillary Clinton.

14) The secret loan and alliance used by the London-listed multinational Glencore in its efforts to secure lucrative mining rights in the Democratic Republic of the Congo.

15) The complex offshore webs used by two Russian billionaires to buy stakes in Arsenal and Everton football clubs.

16) Stars of the BBC hit sitcom Mrs Brown’s Boys used a web of offshore companies to avoid tax.

17) British celebrities including Gary Lineker used an arrangement that let them avoid tax when selling homes in Barbados.

18) Prominent Brexit campaigners have put money offshore.

19) An ex-minister who defended tax avoidance has a Bahamas trust fund.

20) The Dukes of Westminster pumped millions into secretive offshore firms.

21) A tax haven lobby group boasted of ‘superb penetration’ at the top of the UK government before a G8 summit that was expected to bring in greater offshore transparency.

22) The law firm at the centre of the Paradise Papers leak was criticised for 'persistent failures’ on terrorist financing and money laundering rules.

23) Seven Republican super-donors keep money in tax havens.

24) A top Democratic donor built up a vast $8bn private wealth fund in Bermuda.

25) The schemes used to avoid tax on UK property deals.

26) The celebrities, from Harvey Weinstein to Shakira, with offshore interests.

27) How a private equity firm tried to extract £890m from a struggling care home operator by making it take out a costly loan.

28) Trump’s close ally Robert Kraft, the New England Patriots owner, is the longtime owner of an offshore firm.

29) One of the world’s biggest touts used an offshore firm to avoid tax on profits from reselling Adele and Ed Sheeran tickets.

“All external enemies that appear before us are merely projections and judgments created from our own unobserved ‘egoic mind’.”  ~Anon I mus (Spiritually Anonymous)

Shoulder Thursday!

Alternating Cable Shoulder Press:

Move the cables to the bottom of the tower and select an appropriate weight.

·  Grasp the cables and hold them at shoulder height, palms facing forward. This will be your starting position.

·  Keeping your head and chest up, extend through the elbow to press one side directly over head.

·  After pausing at the top, return to the starting position and repeat on the opposite side.