Scientific Fraud Is The Most Baffling Thing Ever To Me Like Do They Think They're Just Going To Make

people don't change as much as you think they do. they mostly become what they already were.

Local man fond of linguistic garden path sentences friends to hearing his boring puns.

shot: all actions are allowed chaser: none are without a price

A storm brewing (Puritan and Cavalier), oil on canvas ― Edgar Bundy (British, 1862-1922)

people should learn more history so that when it comes time to make comparisons it’s not Everything Is Transatlantic Slavery Or The Holocaust

Bruckner Expressway, South Bronx, 1958

NYC Municipal Archives

Virtue doesn't have to be complicated. Nor does it have to be a grand gesture. For example, a virtue could be simple, like doing one thing at a time or cleaning up one mess before making another. If you want a measure for approximating integrity, consider that how you do one thing tends to become how you end up doing everything.

MINIATURIST, Flemish Guillaume de Lorris and Jean de Meung: Romance of the Rose 1490s Manuscript (Harley Ms. 4425) British Library, London

bolting upright with a drawing idea as if i have the energy to do anything but sneeze

Macrophage Defector

Natural killer cells are a type of immune cell that protects the body against not only invading pathogens but also cancer, providing an innate defence against these rogue cells. Some tumours, however, keep natural kill cells at bay and thereby avoid destruction. And recent research in lung tumours reveals this natural killer cell exclusion is achieved with the help of another immune cell – the macrophage. The particular culprit is a type of macrophage covered in a protein called TREM2 – an anti-inflammatory factor. Shown above is a lung tumour (green) packed with TREM2-expressing macrophages (red) that are protecting the cancer from attack. Why these macrophages switch allegiance and side with enemy is unclear, but blocking TREM2 while boosting natural killer cell activity was shown to reduce lung tumour growth in mice suggesting a similar approach might be effective in promoting tumour regression in humans too.

Written by Ruth Williams

Image from work by Matthew D. Park and Ivan Reyes-Torres, and colleagues

Marc and Jennifer Lipschultz Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Image copyright held by the original authors

Research published in Nature Immunology, April 2023

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