Neuroscientists Call For Deep Collaboration To ‘crack’ The Human Brain

Making twisted semiconductors for 3-D projection

A smartphone display that can produce 3-D images will need to be able to twist the light it emits. Now, researchers at the University of Michigan and the Ben-Gurion University of the Negev have discovered a way to mass-produce spiral semiconductors that can do just that.

Back in 1962, University of Michigan engineers E. Leith and J. Upatnieks unveiled realistic 3-D images with the invention of practical holography. The first holographic images of bird on a train were made by creating standing waves of light with bright and dark spots in space, which creates an illusion of material object. It was made possible by controlling polarization and phase of light, i.e. the direction and the timing of electromagnetic wave fluctuations.

The semiconductor helices created by U-M-led team can do exactly that with photons that pass through, reflected from, and emitted by them. They can be incorporated into other semiconductor devices to vary the polarization, phase, and color of light emitted by the different pixels, each of them made from the precisely designed semiconductor helices.

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Glowing crystals can detect, cleanse contaminated drinking water

Tiny, glowing crystals designed to detect and capture heavy-metal toxins such as lead and mercury could prove to be a powerful new tool in locating and cleaning up contaminated water sources.

Motivated by publicized cases in which high levels of heavy metals were found in drinking water in Flint, Mich., and Newark, N.J., a science team led by researchers at Rutgers University used intense X-rays at Lawrence Berkeley National Laboratory (Berkeley Lab) to probe the structure of the crystals they developed and learn how they bind to heavy metals.

The crystals function like miniature, reusable sensors and traps, and are known as luminescent metal-organic frameworks, or LMOFs.

Top performer for detecting and trapping heavy metals

One type of LMOF that the team tested was found to selectively take up more than 99 percent of mercury from a test mixture of heavy and light metals within 30 minutes, according to recent results published in Applied Materials and Interfaces. No other MOFs have performed as well in this dual role of detecting and capturing, or “adsorbing,” toxic heavy metals, the team reported.

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“I always wanted to be a mental health therapist.  Ever since high school, I’ve enjoyed encouraging people and giving them hope.  But I lost my way.  I got caught in a world of addiction.  I lost ten years of my life to drugs.  I stopped when I became pregnant with my child, but by that time it was too late to go back to school.  I started working as an office manager.  I never completely lost my dream.  But I just put it on a shelf for thirty years.  Then five years ago I to…ok it off the shelf.  I heard a lady in my choir talking about how she enrolled in community college.  I drove there the very next day.  I was so nervous when I filled out the application.  I was so nervous the first day of class.  All the old voices were telling me: ‘You never finish anything.’  But I said ‘fuck you’ to the old voices.  And I started getting A’s.  On my first test, I got the only perfect score in the class.  I graduated at the age of 50.  I got my Masters at 55.  And just last night I completed a mental health first aid course.  I’m so close now.  There’s still fear there.  I used to be afraid of it never happening.  Now I’m afraid of it happening.  The old voices try to come back sometimes.  They tell me: ‘You can rest,’ or ‘You’ve earned a break.’  But I’m not stopping this time.  Somebody out there is waiting for me to finish because they need my help.“

Spinal Stimulators Repurposed to Restore Touch in Lost Limb

Imagine tying your shoes or taking a sip of coffee or cracking an egg but without any feeling in your hand. That’s life for users of even the most advanced prosthetic arms.

Although it’s possible to simulate touch by stimulating the remaining nerves in the stump after an amputation, such a surgery is highly complex and individualized. But according to a new study from the University of Pittsburgh’s Rehab Neural Engineering Labs, spinal cord stimulators commonly used to relieve chronic pain could provide a straightforward and universal method for adding sensory feedback to a prosthetic arm.

For this study, published in eLife, four amputees received spinal stimulators, which, when turned on, create the illusion of sensations in the missing arm.

“What’s unique about this work is that we’re using devices that are already implanted in 50,000 people a year for pain — physicians in every major medical center across the country know how to do these surgical procedures — and we get similar results to highly specialized devices and procedures,” said study senior author Lee Fisher, Ph.D., assistant professor of physical medicine and rehabilitation, University of Pittsburgh School of Medicine. 

The strings of implanted spinal electrodes, which Fisher describes as about the size and shape of “fat spaghetti noodles,” run along the spinal cord, where they sit slightly to one side, atop the same nerve roots that would normally transmit sensations from the arm. Since it’s a spinal cord implant, even a person with a shoulder-level amputation can use this device 

Fisher’s team sent electrical pulses through different spots in the implanted electrodes, one at a time, while participants used a tablet to report what they were feeling and where.

All the participants experienced sensations somewhere on their missing arm or hand, and they indicated the extent of the area affected by drawing on a blank human form. Three participants reported feelings localized to a single finger or part of the palm.

“I was pretty surprised at how small the area of these sensations were that people were reporting,” Fisher said. “That’s important because we want to generate sensations only where the prosthetic limb is making contact with objects.”

When asked to describe not just where but how the stimulation felt, all four participants reported feeling natural sensations, such as touch and pressure, though these feelings often were mixed with decidedly artificial sensations, such as tingling, buzzing or prickling.

Although some degree of electrode migration is inevitable in the first few days after the leads are implanted, Fisher’s team found that the electrodes, and the sensations they generated, mostly stayed put across the month-long duration of the experiment. That’s important for the ultimate goal of creating a prosthetic arm that provides sensory feedback to the user. 

“Stability of these devices is really critical,” Fisher said. “If the electrodes are moving around, that’s going to change what a person feels when we stimulate.” 

The next big challenges are to design spinal stimulators that can be fully implanted rather than connecting to a stimulator outside the body and to demonstrate that the sensory feedback can help to improve the control of a prosthetic hand during functional tasks like tying shoes or holding an egg without accidentally crushing it. Shrinking the size of the contacts — the parts of the electrode where current comes out — is another priority. That might allow users to experience even more localized sensations. 

“Our goal here wasn’t to develop the final device that someone would use permanently,” Fisher said. “Mostly we wanted to demonstrate the possibility that something like this could work.”

Austria

Taken By SusanK31

The Boardwalk at Trouville by Claude Monet

The Six Types of Middle-Earth Names

1. Characters whose Names are Secretly Insults: 

Samwise: means “Half-wise” or “Half-wit.” He is Stupid Gamgee

Faramir: Boromir’s name means “steadfast jewel”, but Faramir’s name just means “sufficient jewel.”

Sufficient.

Denethor took one look at baby Faramir and thought “eh I guess he exists or whatever” which is very in character

 2. Characters who Have Way Too Many Names

Examples include Aragorn son of Arathorn son of Arador heir of Isildur Elendil’s son, descendant of Numenor,  Thorongill,  Eagle of the Star,  Dúnadan, Strider,  Wingfoot, Longshanks, Elessar, Edhelharn, Elfstone, Estel (”Hope,”) The Chieftain of the Dúnedain, King of the West, High King of Gondor and Arnor, and Envinyatar the Renewer of the House of Telcontar

Wait I’m sorry did I say “examples” plural Cuz that was all one guy 3. Characters whose parents must’ve been prophets

-Frodo means “wise by experience.” His story is about becoming wise by experience -A lady named Elwing turns into a bird (geddit)

4. Characters whose families were so lazy that they copy-pasted the same first half of a name onto multiple people

Théoden/Théodred  Aragorn/Arathorn/Arador  Éomer/ Éomund/Éowyn/Éorl Elladan/Elrohir/Elrond/Elros/Elwing/Elenwë/Elendil/Eldarion (the laziest family) 

5.Characters whose Names are Expertly Designed so that Newbies can’t Remember Who is Who and Feel Sad

All the people mentioned in number 4 Celeborn, Celegorm, Celebrimbor, Celebrian All the rhyming dwarf names in the Hobbit Sauron and Saruman Arwen and Éowyn

6. Name so nice, you say it twice

Legoas Greenleaf: Legolas’s first name means “Greenleaf” in elvish. Legolas is Greenleaf Greenleaf (thranduil really likes green leaves ok) King Théoden’s name means King in Rohirric. Tolkien decided to name his king “King.” All hail King King  this is what the fanbase means when we say tolkien was a creative genius with language

“She has autonomy. She has a strong will. But she can’t move. So in many ways her life is my life. It’s bigger than me, it controls me, and it makes me fight like never before. We spend so much time together that she’s a part of me. She knows how important she is to me. She had childhood cancer. Her heart failed three times. And I was by her side the entire time. I never realized that I could love someone as much as this. She could never hurt me. She could never hurt anyone. We always ask her: ‘Are you angry?’, ‘Are you mad?’ And she always says ‘no.’ She laughs when I laugh. And right now I’m trying not to cry. Because she’ll cry if I cry.” (São Paulo, Brazil)