Uncharismatic Fact Of The Day

I love this idea.

Can you render the lyrics of Never Gonna Give You Up?

i’ve gotten this request several times now, so for anyone who asked for this after uniquepickles you can just look at this post.

enjoy!:

letter sequence in this ask matching protein-coding amino acids:

WerenstrangerstlveYknwtherlesandsdIdIAfllcmmitmentswhatImthinkingfYwldntgetthisfrmanythergyIstwannatellyhwImfeelingGttamakeynderstandNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyWeveknwneachtherfrslngYrheartseenachingtyretshytsayitsayitInsidewethknwwhatseengingngingnWeknwthegameandweregnnaplayitAndifyaskmehwImfeelingDnttellmeyretlindtseeNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyWeveknwneachtherfrslngYrheartseenachingtyretshytsayitsayitInsidewethknwwhatseengingngingnWeknwthegameandweregnnaplayitIstwannatellyhwImfeelingGttamakeynderstandNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrty

protein guy analysis:

i was really interested to see how this one would turn out, as it is made up almost entirely of repeated domains (the chorus). unfortunately, as many of you may be quick to point out, the chorus of Rick Astley's 'Never Gonna Give You Up' is not in fact a protein domain, and the only thing repeated are some terrible looking loops. i've even included a second picture to properly show you how flat this terrible protein is.

i thought i understood Levinthal's paradox before starting this blog, but these structures are giving me a newfound appreciation. for those who are unaware, Levinthal's paradox is based on the fact that any given protein can fold into an enormous number of possible conformations, but cannot test all of these within the seconds or less that it takes for a protein to fold into its stable tertiary structure. correct folding is controlled by the primary structure (or, the sequence of amino acids encoding the protein) as well as complex factors including the presence of any chaperones to assist with folding, and the relative abundance of the tRNAs matching specific codons for each amino acid. running this blog makes me think of all the ways this process can fail along the way, and all of the almost correct places a protein can get stuck. this one certainly looks like it failed, but even then its hard to believe this is the shape that stuck.

for those interested, the one beta sheet goes with the line 'you wouldn't get this from any other guy', which does only occur once in the song.

predicted protein structure:

🐙 Daily Cephalopod Fact: 🐙

Flamboyant Cuttlefish: Cuttlefish have a specialized, hollow feature called a cuttlebone that helps the animal maintain buoyancy by adjusting the levels of gas and liquid in its chambers.1 Because the flamboyant cuttlefish’s cuttlebone is relatively small, this species can only float and swim for short amounts of time. Instead of swimming, flamboyant cuttlefish “walk” along the ocean floor using their arms. They also have a highly developed sensory system that helps them respond and adjust to their surroundings.

@confidently-regretful

(Sorry to be that guy but) the leaf sheep is not actually a nudibranch, but instead part of the closely related order sacoglossa. Nudibranches are carnivorous while sacoglossa are herbivorous and feed by sucking the sap out of microscopic algae. Many sacoglossa perform a process called kleptoplasty, where they reuse chloroplasts from the algal sap they feed on and implement them into their cells. Some notable examples are the bivalve snails in the family juliidae, the eastern emerald elysia (elysia chlorotica) and obviously the sea sheep. Another slug from the order elysia (elysia rufescens) reuses defensive molecules called kahalalides as well as chloroplasts. Most sacoglossans survive primarily through heterotrophic means (ingesting and digesting) and photosynthesise when food is scarce or unavailable as a last resort. Though research has shown leaf sheep can survive long periods of time with little to no food of heterotrophic or homotrophic (photosynthetic) origin. They store their chloroplasts in cerata, which are structures often found on nudibranches and regularly used for gas exchange or- in blue glaucus’ case- for attack and defence. They also have rhinophores protruding from their face, structures also commonly found on nudibranches, which are chemosensory organs (essentially face tongues) that appear ear like on nudibranches and sacoglossans alike.

To conclude: while leaf sheep are very similar to nudibranches, they belong to the sacoglossan family (which is good because sacoglossans are just as cool) and luckily are not the only animals to photosynthesise.

(I’m researching them for a highschool project and am so obsessed haha)

So not technically a fish but I absolutely love these lil fellas

They’re Nudibranch sea slugs and they all look so pretty!!!!!

Some notable exception are the Sea Bunny (left) which is just the most adorable thing I’ve ever seen

And the Leaf Sheep (right), which is the only animal known to be capable of photosynthesis!

i am SUCH a nudibranch fan oh my god. actual underwater fae creatures. beloved little freak animals. i want to eat them like cereal

do eastern hognoses get attacked by toads a lot? them being immune to their poison seems really specific

Quite the opposite! Many toads secrete toxins to avoid being eaten (most animals don't like eating poisonous food).

However, because they really like eating toads, hognose snakes have evolved specifically to be immune to those toxins. There are many examples of this kind of co-evolution in the animal kingdom (another common one are garter snakes and salamanders).

phys.org

Researchers uncover 500 million-year-old mollusk ancestor

A team of researchers including scientists from the University of Oxford have made an astonishing discovery of a new species of mollusk that

A team of researchers including scientists from the University of Oxford have made an astonishing discovery of a new species of mollusk that lived 500 million years ago. The new fossil, called Shishania aculeata, reveals that the most primitive mollusks were flat, shell-less slugs covered in a protective spiny armor. The findings have been published in the journal Science. The new species was found in exceptionally well-preserved fossils from eastern Yunnan Province in southern China dating from a geological period called the early Cambrian, approximately 514 million years ago. The specimens of Shishania are all only a few centimeters long and are covered in small spikey cones (sclerites) made of chitin, a material also found in the shells of modern crabs, insects, and some mushrooms.

Continue Reading.

Evil biology facts that fill me with Fear :)

hey, I heard y’all like evil biology facts like knowledge about horse blood types.

well! today I was researching alternative biochemistries extraterrestrial life could use and. man. I think Earth life is fucked up enough for me thanks

biological dark matter. WHAT DO YOU MEAN MY BLOOD HAS DNA IN IT FROM NO KNOWN SOURCE. YOU CAN’T JUST SAY THAT COME BACK HERE

One specific cave that has been sealed for 5.5 million years and has developed an ecosystem completely dependent on chemosynthetic bacteria.

Was anybody going to tell me that bacteria have decided iron is yummy and are eating the Titanic, or was I supposed to just read that myself

Terrible Berry (yes, that’s what the genus name means). This whole thing is so fucked up. These scientists were testing whether radiation could be used to kill pathogens in food, so they dosed a tin of meat with enough radiation to kill any known living organism (as one does) but guess what, it still fucking spoiled because of THIS BASTARD FUCKER.

(seriously, why is it like this? WHY has a bacterium evolved to chill in radioactive waste like it’s a soothing Jacuzzi tub? What does it know that we don’t know?)

(ANSWERS. I WANT ANSWERS, YOU CHERNOBYL ASS BITCH.)

Cursed worm, which has no mouth or digestive system and depends entirely on five (5) different species of bacteria, which consume hydrogen sulfide, hydrogen monoxide, and carbon monoxide, for food. How do you, a worm, even...figure out how to do...all that?

Bone worms. At least they like their bones already dead. I still could have gone without knowing this was a thing.

“Oh, parasitic plant, that sounds c—WHAT THE FUCK IS THAT THING”

I am like half convinced this is made up. Seriously, bacteria grow their own electrical wires and we just let them?

Going into 2024 like… 🦀 🖤 😞

Sea stars and friends by Alycia Uyeoka (mostlymarine on Instagram)

quick reminder that my own gay ass genuinely supports the hell outta each and every one of you. regardless if i know you or not, im happy to be living in this shithole of a life in the same world with you.

and im proud of you, i know in my heart just how beautiful, amazing, talented, smart, and worthy you are and i hope you can see that too🏳️‍🌈🌈