Startdoost - Star

I love this idea.

Can you render the lyrics of Never Gonna Give You Up?

i’ve gotten this request several times now, so for anyone who asked for this after uniquepickles you can just look at this post.

enjoy!:

letter sequence in this ask matching protein-coding amino acids:

WerenstrangerstlveYknwtherlesandsdIdIAfllcmmitmentswhatImthinkingfYwldntgetthisfrmanythergyIstwannatellyhwImfeelingGttamakeynderstandNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyWeveknwneachtherfrslngYrheartseenachingtyretshytsayitsayitInsidewethknwwhatseengingngingnWeknwthegameandweregnnaplayitAndifyaskmehwImfeelingDnttellmeyretlindtseeNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyWeveknwneachtherfrslngYrheartseenachingtyretshytsayitsayitInsidewethknwwhatseengingngingnWeknwthegameandweregnnaplayitIstwannatellyhwImfeelingGttamakeynderstandNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrtyNevergnnagiveypNevergnnaletydwnNevergnnarnarndanddesertyNevergnnamakeycryNevergnnasaygdyeNevergnnatellalieandhrty

protein guy analysis:

i was really interested to see how this one would turn out, as it is made up almost entirely of repeated domains (the chorus). unfortunately, as many of you may be quick to point out, the chorus of Rick Astley's 'Never Gonna Give You Up' is not in fact a protein domain, and the only thing repeated are some terrible looking loops. i've even included a second picture to properly show you how flat this terrible protein is.

i thought i understood Levinthal's paradox before starting this blog, but these structures are giving me a newfound appreciation. for those who are unaware, Levinthal's paradox is based on the fact that any given protein can fold into an enormous number of possible conformations, but cannot test all of these within the seconds or less that it takes for a protein to fold into its stable tertiary structure. correct folding is controlled by the primary structure (or, the sequence of amino acids encoding the protein) as well as complex factors including the presence of any chaperones to assist with folding, and the relative abundance of the tRNAs matching specific codons for each amino acid. running this blog makes me think of all the ways this process can fail along the way, and all of the almost correct places a protein can get stuck. this one certainly looks like it failed, but even then its hard to believe this is the shape that stuck.

for those interested, the one beta sheet goes with the line 'you wouldn't get this from any other guy', which does only occur once in the song.

predicted protein structure:

phys.org

Remarkable new plant species steals nutrients from underground fungi

A distinctive plant that steals nutrients from underground fungi has been discovered as a new species by botanists from the Forest Research

A distinctive plant that steals nutrients from underground fungi has been discovered as a new species by botanists from the Forest Research Institute Malaysia (FRIM) in collaboration with local naturalists and stakeholders. The research is published in the journal PhytoKeys. Discovered in the tropical rainforests of Peninsular Malaysia, Thismia malayana belongs to a group of plants known as mycoheterotrophs. Unlike most plants, mycoheterotrophs do not perform photosynthesis. Instead, they act as a parasite, stealing carbon resources from the fungi on their roots. This adaptation takes advantage of the mycorrhizal symbiosis, which is usually a mutually beneficial relationship between colonizing fungi and a plant's root system.

Continue Reading.

ScienceAlert

The Y Chromosome Is Slowly Vanishing. A New Sex Gene May Be The Future of Men.

The sex of human and other mammal babies is decided by a male-determining gene on the Y chromosome.

The sex of human and other mammal babies is decided by a male-determining gene on the Y chromosome. But the human Y chromosome is degenerating and may disappear in a few million years, leading to our extinction unless we evolve a new sex gene. The good news is two branches of rodents have already lost their Y chromosome and have lived to tell the tale. A 2022 paper in Proceedings of the National Academy of Science shows how the spiny rat has evolved a new male-determining gene.

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Going into 2024 like… 🦀 🖤 😞

Photinus fireflies are probably one of North America’s most iconic and beloved beetles, and rightfully so. P. pyralis is big and bright, with a yellow-green color to its bioluminescence

I also often see these smaller Photinus with a warm orange glow. I think they could be P. scintillans, which aligns with their size, flash pattern, the yellow sclerites on males, and where I’m located. females of that species are short-winged and flightless, so I’ll try to find one to figure out the ID for sure.

reminder that fireflies eat slugs and snails as larvae! if you like seeing them in your garden, stop trying to exterminate land gastropods and leave some vegetation where the adults can sleep during the day. slugs and “weeds” = more magic glowing bugs

just found out that giant squid meat is chock fucking full of ammonium ions to increase buoyancy so they would taste fucking disgusting if you tried to make calamari out of them. i mean i wasn't planning on it but a girl can dream right? nobody talk to me

my fish delivered a hot new reaction image