Sympathy Cards For Scientists | @myjetpack

Archstudio. Alley Teahouses- Qulang Hospital. Beijing. China. photos: Archstudio

Living and Working Aboard Station

 Join us on Facebook Live for a conversation with astronaut Kate Rubins and the director of the National Institutes for Health on Tuesday, October 18 at 11:15 a.m. ET.

Astronaut Kate Rubins has conducted out of this world research aboard Earth’s only orbiting laboratory. During her time aboard the International Space Station, she became the first person to sequence DNA in space. On Tuesday, she’ll be live on Facebook with National Institute of Health director Francis Collins, who led the effort to map the human genome. You can submit questions for Kate using the hashtag #SpaceChat on Twitter, or during the live event. Here’s a primer on the science this PhD astronaut has been conducting to help inspire your questions: 

Kate has a background in genomics (a branch of molecular genetics that deals with the study of genomes,specifically the identification and sequencing of their constituent genes and the application of this knowledge in medicine, pharmacy,agriculture, and other fields). When she began her tenure on the station, zero base pairs of DNA had been sequenced in space. Within just a few weeks, she and the Biomolecule Sequencer team had sequenced their one billionth base of DNA aboard the orbital platform.

“I [have a] genomics background, [so] I get really excited about that kind of stuff,” Rubins said in a downlink shortly after reaching the one billion base pairs sequenced goal.

Learn more about this achievement:

+First DNA Sequencing in Space a Game Changer

+Science in Short: One Billion Base Pairs Sequenced

Why is DNA Sequencing in Space a Big Deal?

A space-based DNA sequencer could identify microbes, diagnose diseases and understand crew member health, and potentially help detect DNA-based life elsewhere in the solar system.

+Why Sequencing DNA in Space is a Big Deal

https://youtu.be/1N0qm8HcFRI 

Miss the Reddit AMA on the subject? Here’s a transcript:

+NASA AMA: We just sequenced DNA in space for the first time. Ask us anything! 

NASA and Its Partnerships

We’re not doing this alone. Just like the DNA sequencing was a collaborative project with industry, so is the Eli Lilly Hard to Wet Surfaces investigation, which is a partnership between CASIS and Eli Lilly Co. In this experiment aboard the station, astronauts will study how certain materials used in the pharmaceutical industry dissolve in water while in microgravity. Results from this investigation could help improve the design of tablets that dissolve in the body to deliver drugs, thereby improving drug design for medicines used in space and on Earth. Learn more about what we and our partners are doing:

+Eli Lilly Hard to Wet Surfaces – been happening the last week and a half or so

Researchers to Test How Solids Dissolve in Space to Design Better Tablets and Pills on Earth

With our colleagues at the Stanford University School of Medicine, we’re also investigating the effects of spaceflight on stem cell-derived heart cells, specifically how heart muscle tissue, contracts, grows and changes  in microgravity and how those changes vary between subjects. Understanding how heart muscle cells change in space improves efforts for studying disease, screening drugs and conducting cell replacement therapy for future space missions. Learn more:

+Heart Cells

+Weekly Recap From the Expedition Lead Scientist for Aug. 18, 2016 

It’s Not Just Medicine

Kate and her crew mates have also worked on the combustion experiments.

Kate has also worked on the Bigelow Expandable Activity Module (BEAM), an experimental expandable capsule that docks with the station. As we work on our Journey to Mars, future space habitats  are a necessity. BEAM, designed for Mars or other destinations, is a lightweight and relatively simple to construct solution. Kate has recently examined BEAM, currently attached to the station, to take measurements and install sensors.

Kate recently performed a harvest of the Plant RNA Regulation experiment, by removing seed cassettes and stowing them in cold stowage.

The Plant RNA Regulation investigation studies the first steps of gene expression involved in development of roots and shoots. Scientists expect to find new molecules that play a role in how plants adapt and respond to the microgravity environment of space, which provides new insight into growing plants for food and oxygen supplies on long-duration missions. Read more about the experiment:

+Plant RNA Harvest

NASA Astronaut Kate Rubins is participating in several investigations examining changes in her body as a result of living in space. Some of these changes are similar to issues experienced by our elderly on Earth; for example, bone loss (osteoporosis), cardiovascular deconditioning, immune dysfunction, and muscle atrophy. Understanding these changes and how to prevent them in astronauts off the Earth may help improve health for all of us on the Earth. In additional, the crew aboard station is also working on more generalized studies of aging.

+ Study of the effects of aging on C. elegans, a model organism for a range of biological studies.

2,200 years ago in Turkey, this insane rental agreement was inscribed in stone

Written in Greek, the lease allows renters to use slaves that come with the property

No ripping up this rental agreement. And the punishments for not looking after the property, not paying the rent, etc. Nuts. Plus new legal terminology. Great stuff.

Purchasing power of Europe’s population by 2-digit postcodes, 2016

Vulcanize-Charles Goodyear and the Roman god of Fire

The early nineteenth century saw tremendous advances in chemistry, with scientists leading teams all across the world to improve both science in general and industrial processes in particular.  Leading the charge to improve rubber compounds was Charles Goodyear (born on this day, December 29, 1800, died July 1, 1860) who devoted his life and health to improving rubber compounds.  Self taugh Goodyear ran a hardware store in Philadelphia and realized early that improved rubber goods would transform manufacturing.

He toyed with the chemistry of rubber manufacturing for two decades before hitting upon heating the rubber as the most important part of the process by accident.  He was awarded a patent for vulcanizing rubber in 1844 for his efforts, though he still did not fully understand the process or what exactly was happening.  Enduring backruptcy, jail, and personal tragedy, Goodyear died at the age of 59, collapsing at the news of his daughter’s death and never recovering.  

The verb vulcanize was coined between 1820-1844 (several disputed dates are offered) to describe the process of changing something by adding heat or fire, from Vulcan, the Roman god of Fire.  By 1846, the word was in wide circulation thanks to Goodyear’s patent.  The company that bears his name today was actually founded almost 40 years after his death in honor of his contributions to the science of rubber compounds but also to capitalize on his fame and reputation.  Etymologically, the name Vulcan (Volcānus or Vulcānus) has unclear origins.  Some liguists connect the name with the Cretan god Velchanos, while others dispute this with no clear etymology.  Vulcan’s earliest temple in Rome dates to 8th century BCE.

Image of vulcanization of rubber showing polymer bonds and portrait of Goodyear both in the public domain.  Image of Vulcan at the Forge by Marco Dente (Italian, c. 1493 - 1527) in the public domain, via the National Gallery of Art, Washington, DC.

TODAY IN HISTORY: The retired Space Shuttle Endeavour makes its way to the California Science Center in Los Angeles, October 12, 2012. (The Atlantic)

Farmbot

Open source product is a robotic computer controlled home farming setup to grow your own food:

FarmBot Genesis is humanity’s first open-source CNC farming machine designed for at-home automated food production. 

More Here

I saw them at MIT this year!

Riccardo Yulia

 Rumba Demonstrations