Antibiotic Resistance Has Been Called One Of The Biggest Public Health Threats Of Our Time. There Is

Scientists discover new arsenic-based broad-spectrum antibiotic
"We are running out of tools to fight these diseases. We need a new potent antibiotic to solve this problem," says Yoshinaga, the other co-senior author. "We showed that this new novel arsenic compound can be a potent antibiotic,"

Antibiotic resistance has been called one of the biggest public health threats of our time. There is a pressing need for new and novel antibiotics to combat the rise in antibiotic-resistant bacteria worldwide.

Researchers from Florida International University’s Herbert Wertheim College of Medicine are part of an international team that has discovered a new broad-spectrum antibiotic that contains arsenic. The study, published in Nature’s Communication Biology, is a collaboration between Barry P. Rosen, Masafumi Yoshinaga, Venkadesh Sarkarai Nadar and others from the Department of Cellular Biology and Pharmacology, and Satoru Ishikawa and Masato Kuramata from the Institute for Agro-Environmental Sciences, NARO in Japan.

“The antibiotic, arsinothricin or AST, is a natural product made by soil bacteria and is effective against many types of bacteria, which is what broad-spectrum means,” said Rosen, co-senior author of the study published in the Nature journal, Communications Biology. “Arsinothricin is the first and only known natural arsenic-containing antibiotic, and we have great hopes for it.”

Although it contains arsenic, researchers say they tested AST toxicity on human blood cells and reported that “it doesn’t kill human cells in tissue culture.”

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More Posts from Contradictiontonature and Others

8 years ago

The brilliant colors of a soap film reveal the fluid’s thickness, thanks to a process known as thin film interference. The twisting flow of the film depends on many influences: gravity pulls down on the liquid and tends to make it drain away; evaporation steals fluid from the film; local air currents can push or pull the film; and the variation in the concentration of molecules – specifically the surfactants that stabilize the film – will change the local surface tension, causing flow via the Marangoni effect. Together these and other effects create the dancing turbulence captured above. (Video credit: A. Filipowicz)


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8 years ago
This Year’s Halloween Special Wraps Up The Chemistry Behind Making A Mummy: Http://wp.me/p4aPLT-26m

This year’s Halloween special wraps up the chemistry behind making a mummy: http://wp.me/p4aPLT-26m


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8 years ago
Neuroscientist Captures An MRI Of A Mother And Child

Neuroscientist captures an MRI of a mother and child

Professor Rebecca Saxe (MIT) has taken the first ever MR image of a mother and child. 

“This picture is an MR image of a mother and a child that I made in my lab at MIT. You might see it as sweet and touching… an image of universal love. We can’t see clothes or hairstyles or even skin colour. From what we do see, the biology and the brains, this could be any mother and child or even father and child at any time and place in history; having an experience that any human can recognise.

Or you might see it as disturbing, a reminder that our human bodies are much too fragile as houses for ourselves. MRI’s are usually medical images and often bad news. Each white spot in that picture is a blood vessel that could clog, each tiny fold of those brains could harbour a tumour. The baby’s brain maybe looks particularly vulnerable pressed against the soft thin shell of its skull.

I see those things, universal emotions and frightening fragility but I also see one of the most amazing transformations in biology.”

Quotes have been taken from a TEDx talk given by Professor Saxe explaining the story behind the above picture.


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8 years ago

Who is more humble? The scientist who looks at the universe with an open mind and accepts whatever the universe has to teach us, or somebody who says everything in this book must be considered the literal truth and never mind the fallibility of all the human beings involved?

Carl Sagan


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8 years ago
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living
Feeling A Little Small? Well In The Context Of The Cosmos, We Are Small. We May Just Be Little Guys Living

Feeling a little small? Well in the context of the cosmos, we are small. We may just be little guys living on a speck of dust, afloat in a staggering immensity…

…but we dont think small.


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8 years ago
Meet The All-female Team Of Coders That Brought Us Apollo 11.
Meet The All-female Team Of Coders That Brought Us Apollo 11.

Meet the all-female team of coders that brought us Apollo 11.

In 1969, the world watched as Neil Armstrong marked his historic achievement with the words, “That’s one small step for man, one giant leap for mankind.” His now-famous transmission was heard around the globe thanks to NASA’s Deep Space Network, which made communication from outer space possible.

That network was built by a woman named Susan Finley. She was part of an all-female team of coders whose work was integral to the success of the Apollo 11 mission. Science writer Nathalia Holt brings us their stories in her book, Rise of the Rocket Girls: The Women Who Propelled Us from Missiles to the Moon to Mars.

Listen to their story here.

[Images via NASA]


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8 years ago
Why Do Flowers Do The Thing They Do?
Why Do Flowers Do The Thing They Do?
Why Do Flowers Do The Thing They Do?
Why Do Flowers Do The Thing They Do?
Why Do Flowers Do The Thing They Do?
Why Do Flowers Do The Thing They Do?

Why do flowers do the thing they do?

Flowers are the reproductive organs of plants. When pollinated, flowers develop into fruits containing seeds. However, producing flowers, fruits, and seeds is not easy. Plants devote lots of resources and energy to grow these specialized organs. Thus, plants tend to synchronize their efforts with a time of year when conditions are best for reproductive success and survival.

“Annuals” are plants that grow from seed, flower, and die in one year. Since annuals need to grow leaves and stems before they flower, most annuals won’t mature enough to flower until mid-summer or later.

“Winter annuals” get a jump-start on reproduction by germinating from seeds in the fall, over-wintering as rosettes of leaves and storing energy which allows them to flower early in the spring.

“Perennial” plants can live for many years and flower multiple times. Perennials have evolved many different flowering strategies. Most flower in mid- to late summer after they have had time to accumulate the resources needed to produce seeds each year.  Others, such as early forest wildflowers, grow for only a short while, blooming before the trees above them leaf out, starving them of light. These plants store energy in underground roots or stems, allowing them to flower early and quickly.

The evolution of such diverse flowering strategies is good for plants that otherwise would have to compete for the same resources at the same time. Its also is nice for us, as we get to enjoy flowers brightening the landscape throughout the growing season.

Giffed by: rudescience  From: this video


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8 years ago
Archbishop Ussher’s Chronology Was Taken As Gospel In The Western World. Until We Turned To Another
Archbishop Ussher’s Chronology Was Taken As Gospel In The Western World. Until We Turned To Another
Archbishop Ussher’s Chronology Was Taken As Gospel In The Western World. Until We Turned To Another
Archbishop Ussher’s Chronology Was Taken As Gospel In The Western World. Until We Turned To Another

Archbishop Ussher’s chronology was taken as gospel in the Western world. Until we turned to another book to find the age of the earth, the one that was written in the rocks themselves.


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8 years ago

Most cones don’t really see color

We see color because of specialized light-sensing cells in our eyes called cones. One type, L-cones, sees the reds of strawberries and fire trucks; M-cones detect green leaves, and S-cones let us know the sky is blue. But vision scientists have now discovered that not all cones sense color (see video). The finding was made possible because, for the first time, scientists were able to look at individual photo-sensing cells.


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8 years ago
COLORS OF CHEMISTRY
COLORS OF CHEMISTRY

COLORS OF CHEMISTRY

The bright colors of chemistry fascinate people of all ages. Hriday Bhattacharjee, a Ph.D. student in the lab of Jens Mueller at the University of Saskatchewan, assembled this showcase from compounds he prepared as well as from some synthesized by the undergraduate students he teaches. Organometallic and inorganic chemistry—the study of molecules like these that involve metal atoms—is especially colorful.

The table below the picture indicates the chemicals seen in the photo.

Submitted by Hriday Bhattacharjee

Do science. Take pictures. Win money: Enter our photo contest.


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contradictiontonature - sapere aude
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A pharmacist and a little science sideblog. "Knowledge belongs to humanity, and is the torch which illuminates the world." - Louis Pasteur

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