Congrats Wow! - Blog Posts

Unusual antibiotic killing mechanism we just published in Nature

Our study about the unusual molecular mechanism behind the antibiotic activity of teixobactin can be read open access here: 

https://www.nature.com/articles/s41586-022-05019-y

Figure: The target of teixobactin are bacteria-specific molecules (e.g. they do not exist in human cells) in outer membranes of bacteria. Teixobactin sits on the membrane and aggregates into fibrils, damaging the bacterial membrane and hindering its functions. We got these images by atomic force microscopy that has nanometer resolution. We can see individual teixobactin molecules coming to the bacterial membrane and forming the aggregate.

This is the first star from my research on antibiotics that I started at my postdoc in the Netherlands. More are coming out soon! The very first star was published in Nature, the most read journal in life sciences. I am in scientific heaven!