As someone who has lived with both of these all my life (I live in the Midwest), yes
I just witnessed someone ask for a plant to be identified on facebook and because it had leaves in groups of three, dozens of fully grown adults said "LEAVES OF THREE!!!! POISON IVY!! I CAN SPOT IT ANYWHERE!"........it was not even close to poison ivy. There are multiple plants with leaves "in threes." Thousands and thousands of them. This is like saying any animal with four legs is an alligator.