The X-Files is interesting in this context, since even though Mulder and Scully are our heroes and we love them, they are still FBI agents, actual official representatives of the greater American monoculture who are tasked with going to the backwaters and forgotten places and dealing with the strange and deviant for the good of the whole. To their credit, the people writing The X-Files recognized this, and there’s plenty of episodes where they depict their monsters-of-the-week with some sympathy, or handle Mulder and Scully’s incursions with a note of ambivalence.
Old tv shows where the hero visits the 'town of the week' and identifies then solves a unique problem before moving on are so weird to watch now. "Route 66" to "Touched by an Angel" and etc. Any town in North America that still actually has a unique local culture wouldn't be receptive to an outsider pushing their nose into the local affairs.
Who even still thinks of turning to a pack of kind-hearted outlaws when the bank comes to foreclose on their orphanage?